Oral Solid Dosage Forms:
MHEC is utilized as a binder in tablet formulations, contributing to their mechanical strength and integrity.
It also serves as a disintegrant, promoting the rapid breakup of tablets in the gastrointestinal tract for efficient drug release.
Topical Formulations:
In topical preparations such as gels and creams, MHEC functions as a thickening agent, improving the consistency and spreadability of the formulation.
Ophthalmic Solutions:
MHEC is used in ophthalmic solutions to increase viscosity and prolong corneal contact time, enhancing the therapeutic efficacy of active ingredients.

In general, the gel temperature of HPMC is around 60℃-75℃ depending on its group content and different production technique. Due to the characteristics of MHEC group, it has a higher gel temperature, usually > 80℃. Therefore its stability under high temperature is better that HPMC. In practical construction, in the hot construction environment in summer, the water holding capacity of MHEC with the same viscosity and dosage is better than that of HPMC. Especially in the Southeast Asian countries and India, mortar will sometimes be constructed at high temperature. Cellulose ether with low gel temperature will lose its thickening and water retention at high temperature, thereby accelerating the hardening of mortar, and affects the construction.