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Firstly, the construct grade of HPMC refers to the degree of substitution of hydroxypropyl groups on the cellulose backbone. This parameter affects the solubility and viscosity of the polymer. A higher degree of substitution results in increased solubility and reduced viscosity, whereas a lower degree of substitution leads to decreased solubility and increased viscosity. Therefore, understanding the construct grade is essential for selecting the appropriate HPMC for specific applications.
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HPMC offers several advantages over other polymers due to its unique properties. It provides excellent water retention, increasing the shelf life and stability of products. HPMC also enhances the texture and consistency of products, improving their overall quality. Additionally, HPMC is compatible with a wide range of ingredients and is easy to use in formulations. Its non-toxic and biodegradable nature makes it a safe and sustainable option for various applications.
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- In the pharmaceutical industry, EHEC is recognized for its role as a binder, disintegrant, and coating agent in tablet formulations. Its ability to form films helps in the controlled release of drugs, improving bioavailability and patient compliance. Additionally, it is used as a suspending and thickening agent in syrups and ointments, ensuring consistent product quality.
- Another significant use of HPMC is in controlled-release formulations
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- HPMC is synthesized through a chemical modification process where cellulose, a primary component of plant cell walls, is treated with alkali to form a sodium salt, followed by the reaction with propylene oxide and methanol. The resulting product is a hydrophilic polymer with unique properties, characterized by its ability to dissolve in cold or hot water and form a clear, viscous solution.
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